WebMar 14, 1997 · Two other chloroformate reagents were tested with promazine. In the reaction with 2,2,2-trichloroethyl chloroformate the yield of norpromazine was 38%. … Webphenyl-chloroformate.10 The colorless, crystalline mate-rial 1 effectively reacts with various amines to give the corresponding N-benzyl ureas in excellent yields (Table 1).11 Thus, reaction of cyclohexanemethylamine with 1 in dichloromethane in the presence of triethylamine for 30 min, followed by a basic aqueous workup gives the
Chloroformate - Wikipedia
WebSep 23, 2006 · N-Benzyl tertiary amines on reaction with ethyl chloroformate give the corresponding debenzylated N-carbamates which on treatment with I3B:N(C2H5)2Ph … WebMar 10, 2024 · The fluorogenic reagent 9-fluorenylmethyl chloroformate, also known as 9-fluorenylmethyloxycarbonyl chloride (FMOC-Cl), has advantages of rapid reaction, high detection sensitivity, and ability to derive primary amine and secondary amine compounds [18, 20, 28, 36, 47]. The derivatives are formed in a reaction time of less than 1 min in a ... rowayton trading company
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Webpolymer supported chloroformate resin 9. Bis-trichloromethyl car-bonate (BTC) has been used as a phosgene equivalent to afford a supported chloroformate 9, which on sequential one-pot reaction of variety of alcohols 5 with amines 4 afforded the corresponding carbamates 6 in high yields (Scheme 4). WebNov 15, 2024 · The reaction were initially carried out using NMP as an organic co-solvent to mitigate any solubility issues and was executed by simultaneous addition of the carboxylic acid and amine to the amidation reagent in solution. A range of coupling reagents were shown to afford moderate to high in situ yields. Web14 hours ago · In the case of an in situ substitution of the obtained intermediate the second nucleophile is directly added to the system, and stirred at room temperature for usually … rowayton train parking