Cyclophosphamide alkylating agent
WebCyclophosphamide is an alkylating agent belonging to the group of oxazaphosporines. As cyclophosphamide is in clinical use for more than 40 years, there is a lot of experience … Web2 days ago · Alkylating agents were one first class of drugs to be used against cancer. There exist five traditional categories of alkylating agents, which are given as follows: …
Cyclophosphamide alkylating agent
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WebCyclophosphamide is classified as an alkylating agent. Alkylating agents are most active in the resting phase of the cell. These drugs are cell-cycle non-specific. There are several types of alkylating agents. Note: We strongly encourage you to talk with your health care … WebCyclophosphamide DRUG NAME: Cyclophosphamide SYNONYM: Cyclo, CPA, CPM, CTX, CYC, CYT . COMMON TRADE NAME: CYTOXAN®, 1 PROCYTOX®, NEOSAR® …
WebAlkylating agents such as cisplatiin and cyclophosphamide work by which method of action? They prevent growth by damaging DNA needed for reproduction Which antitumor antibiotic is known to be cardiotoxic and can permanently damage the heart ifgives in high doses? Adriamycin WebCyclophosphamide is an alkylating agent used in antineoplastic and immunosuppressive therapies. Symptomatic hyponatraemia is a rare but life-threatening complication in patients treated with cyclophosphamide.
WebApr 1, 2024 · It belongs to the group of cancer medicines called alkylating agents. Cyclophosphamide is also used for some kinds of kidney disease. Cyclophosphamide … WebCyclophosphamide and cisplatin are two prevalent types of alkylating drugs. Antimetabolites are pharmaceuticals that impede metabolic pathways by blocking the uptake of key growth chemicals by cells. Medications like methotrexate and 5-fluorouracil are examples of antimetabolites.
WebMar 1, 2024 · Cyclophosphamide is contraindicated in patients who have a history of severe hypersensitivity reactions to it, any of its metabolites, or to other components of the product. Anaphylactic reactions including death …
WebThis product is an alkylating, antineoplastic agent, which is converted in the body to an active alkylating metabolite (4-hydroxycyclophosphamide). It possesses marked immunosuppressant properties.1 The dosage of cyclophosphamide in mice for stimulating cell-mediated immunity is 10 mg/kg.2 It has been used for induction chemotherapy to study tandtechnicus sneektandtechnicus schoonhovenWebCyclophosphamide (Cytoxan) Metabolism: The initial metabolic step is mediated primarily by CYP2B6 and involves hydroxylation of the oxazaphosphorine ring to generate a cabinolamine. CYP3A4 also … tandtechnicus rotterdamWebNov 5, 2024 · Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, … tandtechnicus rosmalenWebThe relative alkylating activities of two of the cytotoxic metabolites of cyclophosphamide, phosphoramide mustard and nornitrogen mustard, have been studied at pH 4.6 and 7.4. … tandtechnicus sittardWebSep 29, 2024 · Cyclophosphamide is an alkylating agent that is used in combination with other chemotherapeutic agents for the treatment of a variety of malignant processes. It … tandtechnicus sint truidenWebcyclophosphamide Trade Names Cytoxan cyclophosphamide Therapeutic Class Antineoplastic cyclophosphamide Pharmacologic Class - Alkylating agent - Nitrogen mustard cyclophosphamide Actions - used alone or in combo with other drugs against a wide variety of cancers including: Hodgkin's disease, lymphoma, multiple myeloma, … tandtechnicus temse