2024 Phenytoin hypothermia

Phenytoin hypothermia

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Web7. sep 2024 · Hypothermia is a rare, but potentially fatal adverse effect of antipsychotic drug (APD) use. ... Possible long-acting risperidone-induced hypothermia precipitating phenytoin toxicity in an elderly patient. J Clin Pharm Ther (2011) 36:426–42. 10.1111/j.1365-2710.2010.01189.x ... Web1. jan 2024 · No cause of hypothermia could be identified but as his phenytoin levels normalised, his body temperature also improved. There are three other reported cases of phenytoin- induced hypothermia in the literature. Could this be a rare cause of hypothermia? http://dx.doi.org/10.1136/bcr-2024-227443 Request Permissions

Phenytoin-induced hypothermia. - Abstract - Europe PMC

Web1. júl 2003 · No cause of hypothermia could be identified but as his phenytoin levels normalised, his body temperature also improved. There are three other reported cases of phenytoin- induced... Web1. nov 2006 · The cardiac depressant actions of phenytoin and hypothermia can be additive. Administration of phenytoin in the presence of hypothermia may lead to an adverse cardiac event in children. As phenytoin is a commonly used drug, clinicians need to … my10yearplan

Is phenytoin administration safe in a hypothermic child?

Web1. nov 2006 · Volume 13, Issue 9, November 2006, Pages 953-955. Case report. Is phenytoin administration safe in a hypothermic child? Web15. sep 2024 · Phenytoin (eg, Dilantin) is an anticonvulsant medication used to treat many seizure disorders. It is also a Vaughan-Williams class IB antiarrhythmic agent, although it is now infrequently used for that indication. Phenytoin toxicity is rarely fatal, but can cause neurologic symptoms ranging from nystagmus to ataxia to coma. WebWHO World Health Organization how to pick a mobile phone

Phenytoin elimination in a child during hypothermia for

Web1. jún 2011 · We report the first known case of hypothermia possibly associated with long‐acting risperidone depot injection, precipitating further adverse events secondary to supratherapeutic phenytoin concentrations. View on Wiley ncbi.nlm.nih.gov Save to Library Create Alert Cite 14 Citations Citation Type More Filters Web1. jún 2001 · Europe PMC is an archive of life sciences journal literature. my1020 motor 1000wWebMay reduce serum levels with anticonvulsants (e.g. phenytoin, barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin and other coumarins with prolonged use. ... May cause severe hypothermia with phenothiazine. Contraindications. Paracetamol is contraindicated in patients with severe renal function impairment and hepatic ... how to pick a mortgage lender

"WebThis unintentional significant drop in core body temperature may have resulted in altered metabolism of phenytoin leading to supratherapeutic concentrations and subsequent tonic-clonic seizures, bradycardia and neutropenia. Low core body temperatures can alter the pharmacokinetic profiles of hepatic … " - Phenytoin hypothermia

Phenytoin hypothermia

Therapeutic hypothermia decreases phenytoin elimination in …

Web22. jan 2024 · Search worldwide, life-sciences literature Search. Advanced Search Coronavirus articles and preprints Search examples: "breast cancer" Smith J Web1. jún 2005 · Background: The aim of this study was to describe phenytoin pharmacokinetics in a child during hypothermic management of a traumatic brain injury.Methods: Two children admitted to a paediatric...

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Web14. jan 2024 · Phenytoin TDM is therefore clinically important in the critically ill and should be followed closely. At normal serum levels, patients may experience minor central nervous system depression and adverse effects such as nystagmus, drowsiness, or fatigue. … WebPhenytoin toxicity continues to be a common medical problem. It can present with subtle and atypical symptoms. Herein the authors report what is, to their knowledge, the first case in the literature of phenytoin toxicity that manifested solely in the form of hypothermia.

WebA 60-year-old man with cerebral palsy and epilepsy was admitted with acute lethargy and deterioration in coordination and toxic levels of phenytoin revealed, which could be a rare cause of hypothermia. A 60-year-old man with cerebral palsy and epilepsy was admitted with acute lethargy and deterioration in coordination. He was noted to be hypothermic at … WebTrial-drug vials contained levetiracetam (50 mg per milliliter), fosphenytoin (16.66 mg phenytoin equivalents [mgPE] per milliliter), or valproate (33.33 mg per milliliter).

WebPhenytoin toxicity continues to be a common medical problem. It can present with subtle and atypical symptoms. Herein the authors report what is, to their knowledge, the first case in the literature of phenytoin toxicity that manifested solely in the form of hypothermia. WebThe authors examined the effect of mild therapeutic hypothermia on phenytoin pharmacokinetics in 14 patients with brain damage. Each patient was given phenytoin during and after mild therapeutic hypothermia. Plasma concentrations of total phenytoin, unbound phenytoin, and 5-(p-hydroxyphenyl)-5-pheny …

Web22. jan 2024 · Routine work-up revealed toxic levels of phenytoin. No cause of hypothermia could be identified but as his phenytoin levels normalised, his body temperature also improved. There are three...

Web22. jan 2024 · Phenytoin-induced hypothermia. A 60-year-old man with cerebral palsy and epilepsy was admitted with acute lethargy and deterioration in coordination. He was noted to be hypothermic at 35°C on admission. Routine work-up revealed toxic levels of phenytoin. my1132com my10yearplan student loginWeb19. nov 2024 · The man underwent haemodialysis as per the recommendation and the hypothermia resolved after the first session of haemodialysis. Decrease in the phenytoin concentration with mild improvement in the mental status was also noted. On the admission day 27, his phenytoin concentration was further decreased and his mental status became … my105 race cars for saleWebRandomized control trials demonstrating neuroprotection have employed therapeutic hypothermia at 32–34°C for 12–24 hours in adults and up to 48–72 hours for pediatric patients. Clinical implementation of therapeutic hypothermia can be divided into induction, maintenance and rewarming phases. how to pick a monitorWebPhenytoin elimination in a child during hypothermia for ... - BMJ Group. EN. English Deutsch Français Español Português Italiano Român Nederlands Latina Dansk Svenska Norsk Magyar Bahasa Indonesia Türkçe Suomi Latvian Lithuanian česk ... Phenytoin elimination in a child during hypothermia for ... - BMJ Group my1135comWeb22. jan 2024 · They suggest that phenytoin may produce hypothermia indirectly via induction of hepatic cytochrome P450 enzymes and stimulation of steroid clearance, which could lead to the induction or exacerbation of adrenal insufficiency in certain patients. In the other cases 6 7 no underlying cause such as hypoadrenalism was reported. In all cases ... how to pick a motor controllerWebFosphenytoin is metabolized by CYP2C, has a narrow therapeutic range, and is a commonly used antiepileptic medication. The objective of the study was to evaluate the impact of therapeutic hypothermia on phenytoin levels and pharmacokinetics in … how to pick a monitor for gaming