Phf23 17p
WebWe identify PHF23, encoding an H3K4me3 reader, as a new TSG on chromosome 17p, which is frequently deleted in human cancers. Mechanistically, PHF23 forms a previously unreported histone-modifying complex, the PSH complex, which regulates gene activation through a synergistic link between H3K4me3 and H3K27ac. WebSIGNIFICANCE: We identify PHF23, encoding an H3K4me3 reader, as a new TSG on chromosome 17p, which is frequently deleted in human cancers. Mechanistically, PHF23 forms a previously unreported histone-modifying complex, the PSH complex, which regulates gene activation through a synergistic link between H3K4me3 and H3K27ac.
Phf23 17p
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WebCircular Metric Connectors ST 17P TH 7.5-11mm grip w/ F sockets MA5CAP1700S-S2-KIT; Amphenol SINE Systems; 1: $52.42; 34 In Stock; Mfr. Part # MA5CAP1700S-S2-KIT. Mouser Part # 654-MA5CAP1700SS2KIT. Amphenol SINE Systems: Circular Metric Connectors ST 17P TH 7.5-11mm grip w/ F sockets. Learn More. Datasheet. 34 In Stock: 1: $52.42: 10: … WebIn our body's cells, the PHF23 molecule, PHD finger protein 23, is one of our human genes. ... ⌊ Chromosome 17p genes
Web30. sep 2024 · 综上所述，该研究发现phf23是染色体17p上新的肿瘤抑制基因，phf23与sin3-hdac形成一个新的表观遗传调控的蛋白质机器psh复合物，进而抑制hdac的组蛋白h3k27 … Web25. sep 2024 · Significance We identify PHF23, encoding an H3K4me3 reader, as a new TSG on chromosome 17p, which is frequently deleted in human cancers. Mechanistically, …
Web1. jún 2016 · NUP98-PHF23 fusion shares gene expression signature with NUP98-HOXA9 fusion. RNA sequencing was conducted for the two NUP98-PHF23 positive AML samples … WebAn epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis - epigenetic-mechanism-of-PHF23/README.md at master · pangxueyu233/epigenetic ...
Web22. dec 2024 · Mechanistically, PHF23, a H3K4me3 reader, directly binds and represses the deacetylation activity of the SIN3-HDAC complex through its N-terminus, which …
WebNational Center for Biotechnology Information bobcat behavior habitsWeb2024-10-17 tag:phf23 17p 染色體 腫瘤 缺失 2016年，劉玉、陳崇教授作為共同第一作者，在Nature發表研究論文“Deletions linked to TP53 loss drive cancer through p53-independent mechanisms”，首次證明了... bobcat behavioral characteristicsWebA, NUP98 (top), PHF23 (middle), and the aberrant NP23 fusion protein (bottom). from publication: NUP98-PHF23 Is a Chromatin-Modifying Oncoprotein That Causes a Wide Array of Leukemias Sensitive to ... bobcat beattyville kyWebBecause PHF23 was codeleted with TP53 in human cancers with 17p deletions (3, 8) and loss of both synergistically promoted tumorigenesis (Fig. 2H-J), we wondered if the PSH … bobcat behavioral adaptationsWeb7. feb 2024 · Besides this PHF23-regulated epigenetic mechanism, metabolic alterations have been observed in cancers with del(17p). ALOX15B deficiency leads to accumulation … bobcat bend oregonWeb21. mar 2024 · PHF23 (PHD Finger Protein 23) is a Protein Coding gene. Diseases associated with PHF23 include Myasthenic Syndrome, Congenital, 5 and Charcot-Marie-Tooth Disease, Axonal, Type 2E . An important paralog of this gene is PHF13. UniProtKB/Swiss-Prot Summary for PHF23 Gene bobcat belt toolWebPHF23 has originally been identified as an autophagy-related gene using an approach of functional genomics.20 To follow up, we designed a series of experiments to further explore the poten-tial relationship between PHF23 and autophagy. It was noted that PHF23 overexpression failed to affect the occurrence of bobcat beretta